Meet Inspiring Speakers and Experts at our 3000+ Global Conference Series Events with over 1000+ Conferences, 1000+ Symposiums
and 1000+ Workshops on Medical, Pharma, Engineering, Science, Technology and Business.

Explore and learn more about Conference Series : World's leading Event Organizer

Back

Rocío Gámez-Montaño

Rocío Gámez-Montaño

Universidad de Guanajuato, Mexico

Title: Synthesis of bound-type bis-heterocycles via Groebke-Blackburn-Bienaymé

Biography

Biography: Rocío Gámez-Montaño

Abstract

As a part of our ongoing program to develop short and versatile Groebke-Blackburn-Bienaymé based methodologies towards novel bound-type bis-heterocycles, we are here summarizing our recent published results. Thus, in 2015 we synthesized the series of 18 2-chromone-imidazo[1,2-a]pyridines (a) in 70-93% yield via acid-catalyzed GBBR. Then, in 2016, we synthesized the series of 11 imidazo[2,1-b]thiazoles (b) and 12 benzo[d]fused analogues (c) bound in C-2 position with julolidine, 2-chloroquinoline and chromone heterocyclic frameworks in 82-96% and 72-97% yields respectively, via an acid-free version of the GBBR. As seen, the products herein described may find application in MedChem because they have two heterocyclic frameworks present in many bioactive products and drugs.