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Daphne Mapolelo


Daphne Mapolelo

University of Botswana, Botswana

Biography

Daphne T Mapolelo has expertise in synthesis and spectroscopic characterization of ruthenium metal complexes. My current research interest lies in the synthesis, characterization and biological application of ruthenium polydentate pyridine and benzimidazole-based complexes. The characterization of these ruthenium complexes requires the use of a wide range of spectroscopic/magnetic techniques such as electron paramagnetic resonance (EPR), Nuclear Magnetic Resonance (NMR), MÖssbauer, resonance Raman, natural and magnetically induced circular dichroism (CD and MCD). In addition, in vitro and in vivo studies are employed to test the metal complexes for anticancer, anti HIV and antimicrobial activities.

Abstract

Abstract : Synthesis and characterization of Ru(II)-bis-benzimidazole-based complexes, Ru(III)-polydentate pyridine-based complexes and Ru(II)-bis-benzimidazole polydentate pyridine-based complexes with broad spectrum antimicrobial activity and novel mode of action